The risk gene adenylyl cyclase 2 is associated with bipolar disorder, as has been repeatedly confirmed in genome-wide association studies. However, until now there has not been any proof of a causal ...

A genetic change or variant in a gene called SCN2A is a known cause of infantile seizures, autism spectrum disorder, and intellectual disability, as well as a wide range of other moderate-to-profound ...

Researchers have used AI to uncover the DNA signature of a key genetic “switch” involved in turning genes on. After analyzing ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

Every human gene has to be switched on before its instructions can be read, and for decades one of the most basic parts of that switch has stayed frustratingly blurry. Biologists knew that gene ...

Precise activation of tens of thousands of genes is critical for healthy development and growth. Specialized segments of our ...

(from left) Dr. Buket Basmanav, Nicole Cesarato, Xing Xiong, Prof. Regina Betz and Yasmina Gossmann find causative mutations in the keratin 31 gene for the dominantly-inherited form of monilethrix.

A research team has decoded the genome of historic potato cultivars and used this resource to develop an efficient method for analysis of hundreds of additional potato genomes. A research team has ...

SCN2A related-disorders, although rare in the general population, are one of the more common single-gene neurodevelopmental conditions characterized by infantile seizures, autism spectrum disorder and ...