When the causal mutation is known, the challenge shifts from identifying disease origins to defining its detectable beginning ...

Register studies (Wimberly et al ) reveal the long-lasting educational disadvantage of childhood epilepsy but unexpected sex ...

Background Autosomal dominant Alzheimer’s disease (ADAD) serves as a model for presymptomatic biomarker discovery.

Background We evaluated the seroprevalence of myelin oligodendrocyte glycoprotein immunoglobulin G1 (MOG-IgG) and associated clinical features of patients from a large adult-dominant unselected cohort ...

Objective To determine the prevalence and prognostic value of weight loss (WL) prior to diagnosis in patients with amyotrophic lateral sclerosis (ALS). Methods We enrolled patients diagnosed with ALS ...

Objectives: Bobath based (BB) and movement science based (MSB) physiotherapy interventions are widely used for patients after stroke. There is little evidence to suggest which is most effective. This ...

Background A few case reports have shown controversial results of rituximab efficacy in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Objective To analyse the ...

Correspondence to: Professor Kerry R Mills Department of Clinical Neurophysiology, King’s College Hospital, Denmark Hill, London SE5 9RS, UK; kerry.mills1kingsch.nhs.uk Electromyography (EMG), the ...

Objective Autoantibodies against paranodal proteins have been described in patients with inflammatory neuropathies, but their association with pathology of nodes of Ranvier is unclear. We describe the ...

Functional neurological disorder and somatic symptom disorder are complex neuropsychiatric conditions that have been linked to circuit-based dysfunction of brain networks. Neuromodulation is a novel ...

Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA Dr K C Gorson, Department of Neurology, Caritas St Elizabeth’s Medical Center, 736 Cambridge ...

Ten patients developed peripheral neuropathy while on a reducing diet. One of the patients sustained a severe polyneuropathy attributable to thiamine deficiency. Nine developed unilateral peroneal ...