Rationale Higher blood pressure variability (BPV) has been associated with adverse cardiovascular events in various clinical ...

Background Diagnosing heart failure with preserved ejection fraction (HFpEF) can be challenging because natriuretic peptide ...

Background Chronic total occlusion (CTO) often triggers collateral coronary development, yet the relationship between angiographically graded collaterals and myocardial viability remains incompletely ...

Objective Exercise intolerance is a clinical hallmark of chronic conditions. The present study determined pathophysiological mechanisms of exercise intolerance in cardiovascular, neuromuscular, and ...

Objectives Patients’ backgrounds and clinical outcomes in urgent/emergent/salvage transcatheter aortic valve replacement (Em-TAVR) remain unclear. We investigated patient characteristics and the ...

Objectives Updated knowledge about perioperative myocardial ischaemia (MI) after coronary artery bypass grafting (CABG) and treatment of acute graft failure is needed. We analysed main factors ...

Objective Clinical data on the effect of non-steroidal anti-inflammatory drugs (NSAIDs) in myopericarditis are limited. Since NSAIDs are standard therapy in pericarditis, we retrospectively ...

Spontaneous coronary artery dissection is an increasingly recognised cause of acute coronary syndromes, especially in young and middle-age women. Recognising its particularities and differences with ...

Spirulina, a cyanobacteria commonly referred to as a blue-green algae, is one of the oldest lifeforms on Earth. Spirulina grows in both fresh and saltwater sources and is known for its high protein ...

Background Heterogeneous myocardial contraction is common in myocardial disease and linked to ventricular arrhythmias, but its frequency and relevance in the general population remain unclear. This ...

Background Cardiovascular (CV) disease remains the second leading cause of mortality in Japan, yet real-world estimates of ...

Objective When advising patients about possible initiation of primary prevention treatment, clinicians currently do not have information on expected impact on lifespan, nor how much this increment ...