PROTACs and molecular glues can both remove disease-associated proteins, but choosing between them is not simple. Our new ...

A new review published in the European Journal of Pharmaceutics and Biopharmaceutics argues that no single local ...

Five leading cancer researchers from across genomics, proteomics, cell biology, chemical biology and gene therapy dig into ...

Discover how integrated technologies, multiomic approaches and AI are helping researchers translate complex biological ...

A new preclinical study published has identified BRAF as a key regulator of pain signalling after nerve injury, with existing ...

A new preclinical study finds that combining the antibody-drug conjugate HER3-DXd with PARP inhibitor olaparib significantly ...

AI is making drug discovery faster, but can it make it more successful? Discover why combining AI with systems biology could ...

Researchers at the National University of Singapore have identified DP103 as a potential molecular master switch sustaining ...

An oncology drug abandoned decades ago is getting a second look, with new research uncovering a mechanism that could offer an ...

A large-scale transcriptomic study has pinpointed distinct cell-surface targets for antibody-drug conjugate development ...

Two preclinical studies published in Science Translational Medicine suggest that the binding strength and structural ...

Researchers have engineered human heart organoids complete with functioning valves, creating a physiologically relevant ...