A preclinical study has identified a metabolic vulnerability in aggressive MYC-driven breast cancers, with researchers ...

A structure-guided peptide vaccine targeting PCSK9 has reduced LDL cholesterol and atherosclerotic plaque burden in mouse ...

PROTACs and molecular glues can both remove disease-associated proteins, but choosing between them is not simple. Our new ...

A new review published in the European Journal of Pharmaceutics and Biopharmaceutics argues that no single local ...

St Jude researchers have demonstrated that deleting the Regnase-1 gene from CAR T cells significantly improves tumour control ...

Five leading cancer researchers from across genomics, proteomics, cell biology, chemical biology and gene therapy dig into ...

Discover how integrated technologies, multiomic approaches and AI are helping researchers translate complex biological ...

A new preclinical study published has identified BRAF as a key regulator of pain signalling after nerve injury, with existing ...

AI is making drug discovery faster, but can it make it more successful? Discover why combining AI with systems biology could ...

A new preclinical study finds that combining the antibody-drug conjugate HER3-DXd with PARP inhibitor olaparib significantly ...

Researchers at the National University of Singapore have identified DP103 as a potential molecular master switch sustaining ...

An oncology drug abandoned decades ago is getting a second look, with new research uncovering a mechanism that could offer an ...