A structure-guided peptide vaccine targeting PCSK9 has reduced LDL cholesterol and atherosclerotic plaque burden in mouse ...
PROTACs and molecular glues can both remove disease-associated proteins, but choosing between them is not simple. Our new ...
Five leading cancer researchers from across genomics, proteomics, cell biology, chemical biology and gene therapy dig into ...
A new review published in the European Journal of Pharmaceutics and Biopharmaceutics argues that no single local ...
Discover how integrated technologies, multiomic approaches and AI are helping researchers translate complex biological ...
A new preclinical study published has identified BRAF as a key regulator of pain signalling after nerve injury, with existing ...
Professor Paul O’Reilly is a Professor in Statistical Genetics at the Icahn School of Medicine, Mount Sinai, New York. With a ...
St Jude researchers have demonstrated that deleting the Regnase-1 gene from CAR T cells significantly improves tumour control ...
A new preclinical study finds that combining the antibody-drug conjugate HER3-DXd with PARP inhibitor olaparib significantly ...
A new kidney organoid platform reproduces key features of human acute kidney injury, offering early drug discovery researchers a human-derived system in which to investigate why some kidney cells ...
Dana Watt, PhD is a partner at Breakout Ventures, an investment firm that partners with exceptional founders scaling ...
A first-in-class experimental drug has demonstrated preclinical activity against treatment-resistant blood cancers by ...
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