openheart.bmj

Current Issue

Original research: Operational performance of the 2023 World Heart Federation screening criteria for rheumatic heart disease in a high-risk, resource-limited population (8 July, 2026) ...
Open Heart

Sex differences in blood pressure variability during critical illness: a retrospective cohort study

Rationale Higher blood pressure variability (BPV) has been associated with adverse cardiovascular events in various clinical ...
Open Heart

Natriuretic peptide responses to exercise in HFpEF diagnosis: a pilot study

Background Diagnosing heart failure with preserved ejection fraction (HFpEF) can be challenging because natriuretic peptide ...
openheart.bmj

Prevalence and prognostic implication of iron deficiency and anaemia in patients with severe aortic stenosis

Objective The aim of this study was to evaluate the prevalence and prognostic implication of iron deficiency (ID) and anaemia in patients with severe aortic stenosis (AS). Methods In an observational ...
openheart.bmj

Dobutamine stress echocardiography after positive CCTA: diagnostic performance using fractional flow reserve and instantaneous wave-free ratio as reference standards

Aims To assess the diagnostic accuracy of dobutamine stress echocardiography (DSE) in symptomatic patients with a low to intermediate pretest probability of obstructive coronary artery disease (CAD) ...
openheart.bmj

Emergency interventions for cardiogenic shock due to decompensated aortic stenosis: a systematic review and meta-analysis

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment ...
openheart.bmj

Effectiveness of an impedance cardiography guided treatment strategy to improve blood pressure control in a real-world setting: results from a pragmatic clinical trial

Objective To test the effectiveness of an impedance cardiography (ICG) guided treatment strategy on improving blood pressure (BP) control in real-world clinical practice. Design A single-centre, ...
openheart.bmj

Comparative efficacy and safety of aldosterone synthase inhibitors in hypertension: a Bayesian network meta-analysis of randomised controlled rials

Introduction Resistant hypertension remains a clinical challenge, often linked to elevated aldosterone levels not fully controlled by mineralocorticoid receptor antagonists. Aldosterone synthase ...
openheart.bmj

Combined effect of educational attainment and diabetes on 1-year all-cause mortality in heart failure patients: findings from the National Heart Failure Registry, India

Background Patients with coexisting heart failure (HF) and diabetes mellitus are often prescribed complex treatment regimens, which can contribute to adverse clinical outcomes. However, the impact of ...
openheart.bmj

Factors associated with length of stay among patients with acute myocardial infarction undergoing percutaneous coronary intervention: findings from the CCC-ACS project

Objective Prolonged length of stay (LOS) contributes substantially to the healthcare burden in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI), yet ...
openheart.bmj

Meta-analysis of the diagnostic accuracy of computed tomography angiography compared with invasive coronary angiography in preoperative cardiac surgery planning: a focus on ...

Objective To investigate the diagnostic performance of coronary CT angiography (CCTA) for assessing significant coronary artery disease (CAD) in patients referred for surgical aortic valve replacement ...
openheart.bmj

Nutraceutical activation of Sirt1: a review

The deacetylase sirtuin 1 (Sirt1), activated by calorie restriction and fasting, exerts several complementary effects on cellular function that are favourable to healthspan; it is often thought of as ...